Sorry, but Easy Profile not have this feature. We add this to our TODO list, is a great feature.
You may add some Javascript to do this.
Example (tested and work) add this javascript code to your template or script file
jQuery(document).ready(function($){
$('#jform_alias_of_field input').change(function(){
if($('#jform_alias_of_field input:checked').length==3)
{
$('#jform_alias_of_field input:not(:checked)').attr('disabled','disabled');
}
else
{
$('#jform_alias_of_field input').removeAttr('disabled');
}
});
});
if your field have alias "keywords" replace "jform_alias_of_field" with "jform_keywords"
With this when you have set 3 option, the function disable other options